Isoflavone 7-O-metiltransferasi
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| isoflavone 7-O-metiltransferasi | |
|---|---|
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| Numero EC | 2.1.1.150 |
| Classe | Transferasi |
| Nome sistematico | |
| S-adenosil-L-metionina:idrossiisoflavone 7-O-metiltransferasi | |
| Banche dati | BRENDA, EXPASY, GTD, PDB (RCSB PDB PDBe PDBj PDBsum) |
| Fonte: IUBMB | |
La isoflavone 7-O-metiltransferasi è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione:
- S-adenosil-L-metionina + un 7-idrossiisoflavone ⇄ S-adenosil-L-omocisteina + un 7-metossiisoflavone
L'enzima della alfalfa può metilare la daidzeina, la genisteina ed il 6,7,4'-triidrossiisoflavone, ma non i flavoni o flavanoni.
Bibliografia[modifica | modifica wikitesto]
- Christensen, A.B., Gregersen, P.L., Olsen, C.E. and Collinge, D.B., A flavonoid 7-O-methyltransferase is expressed in barley leaves in response to pathogen attack, in Plant Mol. Biol., vol. 36, 1998, pp. 219–227, Entrez PubMed 9484434.
- Zubieta, C., He, X.-Z., Dixon, R.A. and Noel, J.P., Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases, in Nat. Struct. Biol., vol. 8, 2001, pp. 271–279, Entrez PubMed 11224575.
- Liu, C.-J. and Dixon, R.A., Elicitor-induced association of isoflavone O-methyltransferase with endomembranes prevents the formation and 7-O-methylation of daidzein during isoflavonoid phytoalexin biosynthesis, in Plant Cell, vol. 13, 2001, pp. 2643–2658, Entrez PubMed 11752378.
- He, X.Z., Reddy, J.T. and Dixon, R.A., Stress responses in alfalfa (Medicago sativa L). XXII. cDNA cloning and characterization of an elicitor-inducible isoflavone 7-O-methyltransferase, in Plant Mol. Biol., vol. 36, 1998, pp. 43–54, Entrez PubMed 9484461.
- He, X.-Z. and Dixon, R.A., Affinity chromatography, substrate/product specificity, and amino acid sequence analysis of an isoflavone O-methyltransferase from alfalfa (Medicago sativa L.), in Arch. Biochem. Biophys., vol. 336, 1996, pp. 121–129, Entrez PubMed 8951042.
- He, X.Z. and Dixon, R.A., Genetic manipulation of isoflavone 7-O-methyltransferase enhances biosynthesis of 4′-O-methylated isoflavonoid phytoalexins and disease resistance in alfalfa, in Plant Cell, vol. 12, 2000, pp. 1689–1702, Entrez PubMed 11006341.
- Edwards, R. and Dixon, R.A., Isoflavone O-methyltransferase activities in elicitor-treated cell suspension cultures of Medicago sativa, in Phytochemistry, vol. 30, 1991, pp. 2597–2606.
